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threonine metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-threonine + HCO3- + ATP <=> L-threonylcarbamoyladenylate + diphosphate + H2O 2.7.7.87 L-threonylcarbamoyladenylate synthase

L-threonine + NAD+ <=> L-2-amino-3-oxobutanoate + NADH + H+ 1.1.1.103 L-threonine 3-dehydrogenase

propionate + ATP <=> propanoyl_phosphate + ADP 2.7.2.1 acetate kinase
2.7.2.14 branched-chain-fatty-acid kinase
2.7.2.15 propionate kinase
2.7.2.6 formate kinase
2.7.2.7 butyrate kinase





acetyl-CoA + glycine <=> CoA + 2-amino-3-oxobutanoate 2.3.1.29 glycine C-acetyltransferase

L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP 2.7.2.4 aspartate kinase

L-aspartate_4-semialdehyde + phosphate + NADP+ <=> L-4-aspartyl_phosphate + NADPH + H+ 1.2.1.11 aspartate-semialdehyde dehydrogenase

2-oxobutyrate + oxidized_ferredoxin + CoA <=> propionyl-CoA + reduced_ferredoxin_[iron-sulfur]_cluster + CO2 + H+ 1.2.7.1 pyruvate synthase
1.2.7.11 2-oxoacid oxidoreductase (ferredoxin)
1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)



O-phospho-L-homoserine + H2O <=> phosphate + L-threonine 4.2.3.1 threonine synthase

L-threonine <=> glycine + acetaldehyde 4.1.2.26 phenylserine aldolase
4.1.2.42 D-threonine aldolase
4.1.2.48 low-specificity L-threonine aldolase
4.1.2.5 L-threonine aldolase




aminoacetone + H2O + O2 <=> methylglyoxal + NH3 + H2O2 1.4.3.21 primary-amine oxidase
1.4.3.4 monoamine oxidase


ATP + L-threonine + tRNAMet <=> AMP + diphosphate + L-threonyl-tRNAThr 6.1.1.3 threonine---tRNA ligase

2-oxobutyrate + CoA <=> propionyl-CoA + formate 2.3.1
2.3.1.54 formate C-acetyltransferase


L-threonylcarbamoyladenylate + adenine37_in_tRNA <=> N6-L-threonylcarbamoyladenine37_in_tRNA + AMP + H+ 2.3.1.234 N6-L-threonylcarbamoyladenine synthase

propionyl-CoA + phosphate <=> propanoyl_phosphate + CoA 2.3.1.19 phosphate butyryltransferase
2.3.1.222 phosphate propanoyltransferase
2.3.1.8 phosphate acetyltransferase



L-homoserine + ATP <=> H+ + O-phospho-L-homoserine + ADP 2.7.1.39 homoserine kinase

acetaldehyde + CoA + NAD+ <=> acetyl-CoA + NADH + H+ 1.2.1.10 acetaldehyde dehydrogenase (acetylating)
1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.57 butanal dehydrogenase
1.2.1.87 propanal dehydrogenase (CoA-propanoylating)




L-2,4-diaminobutanoate + 2-oxoglutarate <=> L-aspartate_4-semialdehyde + L-glutamate 2.6.1.46 diaminobutyrate---pyruvate transaminase
2.6.1.76 diaminobutyrate---2-oxoglutarate transaminase
4.1.1.86 diaminobutyrate decarboxylase



L-threonine <=> 2-oxobutyrate + NH3 4.2.3.1 threonine synthase
4.3.1.17 L-serine ammonia-lyase
4.3.1.19 threonine ammonia-lyase



L-homoserine + NADP+ <=> L-aspartate_4-semialdehyde + NADPH + H+ 1.1.1.3 homoserine dehydrogenase

L-homoserine + acetyl-CoA <=> O-acetyl-L-homoserine + CoA 2.3.1.31 homoserine O-acetyltransferase

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